elynx-tree-0.4.0: src/ELynx/Tree/Distribution/TimeOfOriginNearCritical.hs
{-# LANGUAGE DeriveDataTypeable #-}
{-# LANGUAGE DeriveGeneric #-}
-- |
-- Module : ELynx.Tree.Distribution.TimeOfOriginNearCritical
-- Description : Distribution of time of origin for birth and death trees
-- Copyright : (c) Dominik Schrempf 2018
-- License : GPL-3.0-or-later
--
-- Maintainer : dominik.schrempf@gmail.com
-- Stability : unstable
-- Portability : portable
--
-- Creation date: Tue Feb 13 13:16:18 2018.
--
-- See Gernhard, T. (2008). The conditioned reconstructed process. Journal of
-- Theoretical Biology, 253(4), 769–778. http://doi.org/10.1016/j.jtbi.2008.04.005.
--
-- Distribution of the time of origin for birth and death trees. See corollary 3.3
-- in the paper cited above.
module ELynx.Tree.Distribution.TimeOfOriginNearCritical
( TimeOfOriginNearCriticalDistribution (..),
cumulative,
density,
quantile,
)
where
import Data.Data
( Data,
Typeable,
)
import ELynx.Tree.Distribution.Types
import GHC.Generics (Generic)
import qualified Statistics.Distribution as D
-- | Distribution of the time of origin for a phylogenetic tree evolving under
-- the birth and death process and conditioned on observing n leaves today.
data TimeOfOriginNearCriticalDistribution = TONCD
{ -- | Number of leaves of the tree.
todTN :: Int,
-- | Birth rate.
todLa :: Rate,
-- | Death rate.
todMu :: Rate
}
deriving (Eq, Typeable, Data, Generic)
instance D.Distribution TimeOfOriginNearCriticalDistribution where
cumulative = cumulative
-- | Cumulative distribution function; see Mathematica notebook.
cumulative :: TimeOfOriginNearCriticalDistribution -> Time -> Double
cumulative (TONCD n' l m) t
| t <= 0 = 0
| otherwise = t1 + t2
where
d = l - m
n = fromIntegral n'
t1 = (t * l / (1.0 + t * l)) ** n
t2 = (n * t * t1) * d / (2.0 * (1.0 + t * l))
instance D.ContDistr TimeOfOriginNearCriticalDistribution where
density = density
quantile = quantile
-- | The density function Eq. (5).
density :: TimeOfOriginNearCriticalDistribution -> Time -> Double
density (TONCD n' l m) t
| t < 0 = 0
| otherwise = nom / den
where
n = fromIntegral n'
nom =
n * (t * l / (1 + t * l)) ** n * (2 + (3 + n) * t * l - (1 + n) * t * m)
den = 2 * t * (1 + t * l) ** 2
-- | The inverted cumulative probability distribution 'cumulative'. See also
-- 'D.ContDistr'.
quantile :: TimeOfOriginNearCriticalDistribution -> Double -> Time
quantile (TONCD n' l m) p
| p >= 0 && p <= 1 =
t1 + t2nom / t2den
| otherwise =
error $
"PointProcess.quantile: p must be in [0,1] range. Got: "
++ show p
++ "."
where
n = fromIntegral n'
t1 = - p ** (1 / n) / ((-1 + p ** (1 / n)) * l)
t2nom = p ** (2 / n) * (m - l)
t2den = 2 * (-1 + p ** (1 / n)) ** 2 * l ** 2
instance D.ContGen TimeOfOriginNearCriticalDistribution where
genContVar = D.genContinuous