packages feed

elynx 0.2.1 → 0.2.2

raw patch · 4 files changed

+374/−99 lines, 4 filesdep ~elynx-toolsdep ~slynxdep ~tlynx

Dependency ranges changed: elynx-tools, slynx, tlynx

Files

ChangeLog.md view
@@ -1,10 +1,13 @@ -# Table of Contents--1.  [Changelog for ELynx](#orgbba4466)+# Changelog for ELynx  -<a id="orgbba4466"></a>+## Version 0.2.2 -# Changelog for ELynx+-   Validation and repetition of previous analyses is finally possible with the+    new `elynx` binary.+-   A library `elynx-markov` for running Markov processes along phylogenetic trees+    has been split off `elynx-seq`. This library performs the computations when+    executing `slynx simulate ...`.+-   Many other small improvements. 
README.md view
@@ -2,18 +2,17 @@  # The ELynx Suite -Version: 0.1.0.+Version: 0.2.2. Reproducible evolution made easy. -The ELynx Suite is a Haskell library and a tool set for computational biology.-The goal of the ELynx Suite is reproducible research. Evolutionary sequences and-phylogenetic trees can be read, viewed, modified and simulated. Exact-specification of all options is necessary, and nothing is assumed about the data-(e.g., the type of the genetic code). The command line with all arguments is-consistently, and automatically logged. The work overhead in the beginning-usually pays off in the end.+A Haskell library and tool set for computational biology. The goal of ELynx is+reproducible research. Evolutionary sequences and phylogenetic trees can be+read, viewed, modified and simulated. The command line with all arguments is+logged consistently, and automatically. Data integrity is verified using SHA256+sums so that validation of past analyses is possible without the need to+recompute the result. -The Elynx Suite consists of four library packages and two executables providing+The Elynx Suite consists of four library packages and three executables providing a range of sub commands.  The library packages are:@@ -25,8 +24,9 @@  The executables are: --   **slynx:** Analyze, modify, and simulate evolutionary sequences (FASTA format).--   **tlynx:** Analyze, modify, and simulate phylogenetic trees (Newick format).+-   **slynx:** Analyze, modify, and simulate evolutionary sequences.+-   **tlynx:** Analyze, modify, and simulate phylogenetic trees.+-   **elynx:** Validate and redo past analyses.  **ELynx is actively developed. We happily receive comments, ideas, feature requests, and pull requests!**@@ -68,10 +68,11 @@      slynx --help -    ELynx Suite version 0.1.0. Developed by Dominik Schrempf. Compiled on March 21,-    2020, at 16:37 pm, UTC.+    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.     -    Usage: slynx [-v|--verbosity VALUE] [-o|--output-file-basename NAME]+    Usage: slynx [-v|--verbosity VALUE] [-o|--output-file-basename NAME]                   [-f|--force] COMMAND       Analyze, and simulate multi sequence alignments.     @@ -87,18 +88,17 @@          Available commands:       concatenate              Concatenate sequences found in input files.-      examine                  Examine sequences. If data is a multi sequence-                               alignment, additionally analyze columns.+      examine                  Examine sequences. If data is a multi sequence alignment, additionally analyze columns.       filter-columns           Filter columns of multi sequence alignments.       filter-rows              Filter rows (or sequences) found in input files.       simulate                 Simulate multi sequence alignments.       sub-sample               Sub-sample columns from multi sequence alignments.       translate                Translate from DNA to Protein or DNAX to ProteinX.     -    File formats:+    Available sequence file formats:       - FASTA     -    Alphabet types:+    Available alphabets:       - DNA (nucleotides)       - DNAX (nucleotides; including gaps)       - DNAI (nucleotides; including gaps, and IUPAC codes)@@ -107,19 +107,20 @@       - ProteinS (amino acids; including gaps, and translation stops)       - ProteinI (amino acids; including gaps, translation stops, and IUPAC codes)     -    The ELynx Suite-    ----------------    A Haskell library and a tool set for computational biology. The goal of the-    ELynx Suite is reproducible research. Evolutionary sequences and phylogenetic-    trees can be read, viewed, modified and simulated. Exact specification of all-    options is necessary, and nothing is assumed about the data (e.g., the type of-    code). The command line with all arguments is consistently, and automatically-    logged.+    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.          slynx     Analyze, modify, and simulate evolutionary sequences.     tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.     -    Get help for specific commands:+    Get help for sub commands:       slynx examine --help  @@ -129,13 +130,36 @@      slynx concatenate --help +    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.+         Usage: slynx concatenate (-a|--alphabet NAME) INPUT-FILE       Concatenate sequences found in input files.          Available options:+      -h,--help                Show this help text+      -V,--version             Show version       -a,--alphabet NAME       Specify alphabet type NAME       INPUT-FILE               Read sequences from INPUT-FILE       -h,--help                Show this help text+    +    +    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.+    +    slynx     Analyze, modify, and simulate evolutionary sequences.+    tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.+    +    Get help for sub commands:+      slynx examine --help   ## Examine@@ -144,15 +168,37 @@      slynx examine --help -    Usage: slynx examine (-a|--alphabet NAME) [INPUT-FILE] [--per-site]-      Examine sequences. If data is a multi sequence alignment, additionally analyze-      columns.+    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.     +    Usage: slynx examine (-a|--alphabet NAME) INPUT-FILE [--per-site]+      Examine sequences. If data is a multi sequence alignment, additionally analyze columns.+         Available options:+      -h,--help                Show this help text+      -V,--version             Show version       -a,--alphabet NAME       Specify alphabet type NAME       INPUT-FILE               Read sequences from INPUT-FILE       --per-site               Report per site summary statistics       -h,--help                Show this help text+    +    +    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.+    +    slynx     Analyze, modify, and simulate evolutionary sequences.+    tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.+    +    Get help for sub commands:+      slynx examine --help   ## Filter@@ -161,12 +207,17 @@      slynx filter-rows --help -    Usage: slynx filter-rows (-a|--alphabet NAME) [INPUT-FILE]-                             [--longer-than LENGTH] [--shorter-than LENGTH]-                             [--standard-characters]+    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.+    +    Usage: slynx filter-rows (-a|--alphabet NAME) INPUT-FILE [--longer-than LENGTH] +                             [--shorter-than LENGTH] [--standard-characters]       Filter rows (or sequences) found in input files.          Available options:+      -h,--help                Show this help text+      -V,--version             Show version       -a,--alphabet NAME       Specify alphabet type NAME       INPUT-FILE               Read sequences from INPUT-FILE       --longer-than LENGTH     Only keep sequences longer than LENGTH@@ -174,21 +225,61 @@       --standard-characters    Only keep sequences containing at least one standard                                (i.e., non-IUPAC) character       -h,--help                Show this help text+    +    +    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.+    +    slynx     Analyze, modify, and simulate evolutionary sequences.+    tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.+    +    Get help for sub commands:+      slynx examine --help  Filter columns of multi sequence alignments with `filter-columns`.      slynx filter-columns --help -    Usage: slynx filter-columns (-a|--alphabet NAME) [INPUT-FILE]+    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.+    +    Usage: slynx filter-columns (-a|--alphabet NAME) INPUT-FILE                                  [--standard-chars DOUBLE]-      Filter columns of multi-sequence alignments.+      Filter columns of multi sequence alignments.          Available options:+      -h,--help                Show this help text+      -V,--version             Show version       -a,--alphabet NAME       Specify alphabet type NAME       INPUT-FILE               Read sequences from INPUT-FILE       --standard-chars DOUBLE  Keep columns with a proportion standard (non-IUPAC)                                characters larger than DOUBLE in [0,1]       -h,--help                Show this help text+    +    +    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.+    +    slynx     Analyze, modify, and simulate evolutionary sequences.+    tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.+    +    Get help for sub commands:+      slynx examine --help   ## Simulate@@ -197,16 +288,22 @@      slynx simulate --help -    Usage: slynx simulate (-t|--tree-file Name) [-s|--substitution-model MODEL]-                          [-m|--mixture-model MODEL] [-e|--edm-file NAME]-                          [-p|--siteprofile-files NAMES]-                          [-w|--mixture-model-weights "[DOUBLE,DOUBLE,...]"]+    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.+    +    Usage: slynx simulate (-t|--tree-file Name) [-s|--substitution-model MODEL] +                          [-m|--mixture-model MODEL] [-e|--edm-file NAME] +                          [-p|--siteprofile-files NAMES] +                          [-w|--mixture-model-weights "[DOUBLE,DOUBLE,...]"]                            [-g|--gamma-rate-heterogeneity "(NCAT,SHAPE)"]                           (-l|--length NUMBER) [-S|--seed [INT]]       Simulate multi sequence alignments.          Available options:-      -t,--tree-file Name      Read trees from file NAME+      -h,--help                Show this help text+      -V,--version             Show version+      -t,--tree-file Name      Read tree from Newick file NAME       -s,--substitution-model MODEL                                Set the phylogenetic substitution model; available                                models are shown below (mutually exclusive with -m@@ -228,17 +325,24 @@          Substitution models:     -s "MODEL[PARAMETER,PARAMETER,...]{STATIONARY_DISTRIBUTION}"-       Supported DNA models: JC, HKY.+       Supported DNA models: JC, F81, HKY, GTR4.          For example,            -s HKY[KAPPA]{DOUBLE,DOUBLE,DOUBLE,DOUBLE}-       Supported Protein models: Poisson, Poisson-Custom, LG, LG-Custom, WAG, WAG-Custom.+           -s GTR4[e_AC,e_AG,e_AT,e_CG,e_CT,e_GT]{DOUBLE,DOUBLE,DOUBLE,DOUBLE}+              where the 'e_XY' are the exchangeabilities from nucleotide X to Y.+       Supported Protein models: Poisson, Poisson-Custom, LG, LG-Custom, WAG, WAG-Custom, GTR20.          MODEL-Custom means that only the exchangeabilities of MODEL are used,          and a custom stationary distribution is provided.          For example,+           -s LG            -s LG-Custom{...}+           -s GTR20[e_AR,e_AN,...]{...}+              the 'e_XY' are the exchangeabilities from amino acid X to Y (alphabetical order).+       Notes: The F81 model for DNA is equivalent to the Poisson-Custom for proteins.+              The GTR4 model for DNA is equivalent to the GTR20 for proteins.          Mixture models:-    -m "MIXTURE(SUBSTITUTION_MODEL_1,SUBSTITUTION_MODEL_2)"+    -m "MIXTURE(SUBSTITUTION_MODEL_1,SUBSTITUTION_MODEL_2[PARAMETERS]{STATIONARY_DISTRIBUTION},...)"        For example,          -m "MIXTURE(JC,HKY[6.0]{0.3,0.2,0.2,0.3})"     Mixture weights have to be provided with the -w option.@@ -253,6 +357,22 @@          LG exchangeabilities with stationary distributions given in FILE.          -m "EDM(LG-Custom)" -e FILE     For special mixture models, mixture weights are optional.+    +    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.+    +    slynx     Analyze, modify, and simulate evolutionary sequences.+    tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.+    +    Get help for sub commands:+      slynx examine --help   ## Sub-sample@@ -261,12 +381,18 @@      slynx sub-sample --help -    Usage: slynx sub-sample (-a|--alphabet NAME) [INPUT-FILE]+    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.+    +    Usage: slynx sub-sample (-a|--alphabet NAME) INPUT-FILE                             (-n|--number-of-sites INT)                             (-m|--number-of-alignments INT) [-S|--seed [INT]]       Sub-sample columns from multi sequence alignments.          Available options:+      -h,--help                Show this help text+      -V,--version             Show version       -a,--alphabet NAME       Specify alphabet type NAME       INPUT-FILE               Read sequences from INPUT-FILE       -n,--number-of-sites INT Number of sites randomly drawn with replacement@@ -276,8 +402,23 @@                                integers with up to 256 elements (default: random)       -h,--help                Show this help text     -    Create a given number of multi sequence alignments, each of which contains a-    given number of random sites drawn from the original multi sequence alignment.+    Create a given number of multi sequence alignments, each of which contains a given number of random sites drawn from the original multi sequence alignment.+    +    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.+    +    slynx     Analyze, modify, and simulate evolutionary sequences.+    tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.+    +    Get help for sub commands:+      slynx examine --help   ## Translate@@ -286,17 +427,40 @@      slynx translate --help -    Usage: slynx translate (-a|--alphabet NAME) [INPUT-FILE]-                           (-r|--reading-frame INT) (-u|--universal-code CODE)+    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.+    +    Usage: slynx translate (-a|--alphabet NAME) INPUT-FILE (-r|--reading-frame INT)+                           (-u|--universal-code CODE)       Translate from DNA to Protein or DNAX to ProteinX.          Available options:+      -h,--help                Show this help text+      -V,--version             Show version       -a,--alphabet NAME       Specify alphabet type NAME       INPUT-FILE               Read sequences from INPUT-FILE       -r,--reading-frame INT   Reading frame [0|1|2].       -u,--universal-code CODE universal code; one of: Standard,                                VertebrateMitochondrial.       -h,--help                Show this help text+    +    +    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.+    +    slynx     Analyze, modify, and simulate evolutionary sequences.+    tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.+    +    Get help for sub commands:+      slynx examine --help   # TLynx@@ -305,10 +469,11 @@      tlynx --help -    ELynx Suite version 0.1.0. Developed by Dominik Schrempf. Compiled on March 21,-    2020, at 16:37 pm, UTC.+    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.     -    Usage: tlynx [-v|--verbosity VALUE] [-o|--output-file-basename NAME]+    Usage: tlynx [-v|--verbosity VALUE] [-o|--output-file-basename NAME]                   [-f|--force] COMMAND       Compare, examine, and simulate phylogenetic trees.     @@ -323,37 +488,33 @@                                output files.          Available commands:-      coalesce                 Simulate phylogenetic trees using the coalescent-                               processes (see also the 'simulate' command for-                               simulations using the birth and death process).-      compare                  Compare two phylogenetic trees (compute distances and-                               branch-wise differences).-      connect                  Connect two phylogenetic trees in all ways (possibly-                               honoring constraints).+      coalesce                 Simulate phylogenetic trees using the coalescent processes (see also the 'simulate' command for simulations using the birth and death process).+      compare                  Compare two phylogenetic trees (compute distances and branch-wise differences).+      connect                  Connect two phylogenetic trees in all ways (possibly honoring constraints).       distance                 Compute distances between many phylogenetic trees.       examine                  Compute summary statistics of phylogenetic trees.-      shuffle                  Shuffle a phylogenetic tree (keep coalescent times,-                               but shuffle topology and leaves).-      simulate                 Simulate phylogenetic trees using birth and death-                               processes (see also the 'coalesce' command for-                               simulations using the coalescent process).+      shuffle                  Shuffle a phylogenetic tree (keep coalescent times, but shuffle topology and leaves).+      simulate                 Simulate phylogenetic trees using birth and death processes (see also the 'coalesce' command for simulations using the coalescent process).     -    File formats:-      - Newick+    Available tree file formats:+      - Newick Standard: Branch support values are stored in square brackets after branch lengths.+      - Newick IqTree:   Branch support values are stored as node names after the closing bracket of forests.+      - Newick RevBayes  Key-value pairs is provided in square brackets after node names as well as branch lengths. XXX: Key value pairs are IGNORED at the moment.     -    The ELynx Suite-    ----------------    A Haskell library and a tool set for computational biology. The goal of the-    ELynx Suite is reproducible research. Evolutionary sequences and phylogenetic-    trees can be read, viewed, modified and simulated. Exact specification of all-    options is necessary, and nothing is assumed about the data (e.g., the type of-    code). The command line with all arguments is consistently, and automatically-    logged.+    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.          slynx     Analyze, modify, and simulate evolutionary sequences.     tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.     -    Get help for specific commands:+    Get help for sub commands:       slynx examine --help  @@ -363,18 +524,43 @@      tlynx compare --help -    Usage: tlynx compare [-n|--normalize] [-b|--bipartitions] [-i|--newick-iqtree]-                         NAME-      Compare two phylogenetic trees (compute distances and branch-wise-      differences).+    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.     +    Usage: tlynx compare [-n|--normalize] [-b|--bipartitions] [-t|--intersect] +                         [-f|--newick-format FORMAT] NAME+      Compare two phylogenetic trees (compute distances and branch-wise differences).+         Available options:+      -h,--help                Show this help text+      -V,--version             Show version       -n,--normalize           Normalize trees before comparison-      -b,--bipartitions        Print common and missing bipartitions-      -i,--newick-iqtree       Use IQ-TREE Newick format (internal node labels are-                               branch support values)+      -b,--bipartitions        Print and plot common and missing bipartitions+      -t,--intersect           Compare intersections; i.e., before comparison, drop+                               leaves that are not present in the other tree+      -f,--newick-format FORMAT+                               Newick tree format; see 'tlynx+                               --help' (default: Standard)       NAME                     Tree file       -h,--help                Show this help text+    +    +    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.+    +    slynx     Analyze, modify, and simulate evolutionary sequences.+    tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.+    +    Get help for sub commands:+      slynx examine --help   ## Examine@@ -383,14 +569,38 @@      tlynx examine --help -    Usage: tlynx examine [INPUT-FILE] [-i|--newick-iqtree]+    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.+    +    Usage: tlynx examine INPUT-FILE [-f|--newick-format FORMAT]       Compute summary statistics of phylogenetic trees.          Available options:+      -h,--help                Show this help text+      -V,--version             Show version       INPUT-FILE               Read trees from INPUT-FILE-      -i,--newick-iqtree       Use IQ-TREE Newick format (internal node labels are-                               branch support values)+      -f,--newick-format FORMAT+                               Newick tree format; see 'tlynx+                               --help' (default: Standard)       -h,--help                Show this help text+    +    +    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.+    +    slynx     Analyze, modify, and simulate evolutionary sequences.+    tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.+    +    Get help for sub commands:+      slynx examine --help   ## Simulate@@ -399,13 +609,19 @@      tlynx simulate --help -    Usage: tlynx simulate [-t|--nTrees INT] [-n|--nLeaves INT] [-H|--height DOUBLE]-                          [-M|--condition-on-mrca] [-l|--lambda DOUBLE]-                          [-m|--mu DOUBLE] [-r|--rho DOUBLE] [-u|--sub-sample]+    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.+    +    Usage: tlynx simulate [-t|--nTrees INT] [-n|--nLeaves INT] [-H|--height DOUBLE] +                          [-M|--condition-on-mrca] [-l|--lambda DOUBLE] +                          [-m|--mu DOUBLE] [-r|--rho DOUBLE] [-u|--sub-sample]                            [-s|--summary-statistics] [-S|--seed [INT]]-      Simulate phylogenetic trees using birth and death processes.+      Simulate phylogenetic trees using birth and death processes (see also the 'coalesce' command for simulations using the coalescent process).          Available options:+      -h,--help                Show this help text+      -V,--version             Show version       -t,--nTrees INT          Number of trees (default: 10)       -n,--nLeaves INT         Number of leaves per tree (default: 5)       -H,--height DOUBLE       Fix tree height (no default)@@ -424,8 +640,63 @@     Summary statistics only: only print (NumberOfExtantChildren BranchLength) pairs for each branch of each tree. The trees are separated by a newline character.     Sub-sampling: simulate one big tree with n'=round(n/rho), n'>=n, leaves, and randomly sample sub-trees with n leaves. Hence, with rho=1.0, the same tree is reported over and over again.     Gernhard, T. (2008). The conditioned reconstructed process. Journal of Theoretical Biology, 253(4), 769–778. http://doi.org/10.1016/j.jtbi.2008.04.005+    +    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.+    +    slynx     Analyze, modify, and simulate evolutionary sequences.+    tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.+    +    Get help for sub commands:+      slynx examine --help  +# ELynx++Validate and (optionally) redo past ELynx analyses.++    elynx --help++    ELynx Suite version 0.2.1.+    Developed by Dominik Schrempf.+    Compiled on April 27, 2020, at 12:08 pm, UTC.+    +    Usage: elynx COMMAND+      Validate and redo past ELynx analyses+    +    Available options:+      -h,--help                Show this help text+      -V,--version             Show version+    +    Available commands:+      validate                 Validate an ELynx analysis+      redo                     Redo an ELynx analysis+    +    +    ELynx+    -----+    A Haskell library and tool set for computational biology. The goal of ELynx is+    reproducible research. Evolutionary sequences and phylogenetic trees can be+    read, viewed, modified and simulated. The command line with all arguments is+    logged consistently, and automatically. Data integrity is verified using SHA256+    sums so that validation of past analyses is possible without the need to+    recompute the result.+    +    slynx     Analyze, modify, and simulate evolutionary sequences.+    tlynx     Analyze, modify, and simulate phylogenetic trees.+    elynx     Validate and redo past analyses.+    +    Get help for sub commands:+      slynx examine --help++ # Library documentation  Documentation of the libraries can be found on [Hackage](https://hackage.haskell.org/):@@ -435,8 +706,9 @@ -   [elynx-tools](https://hackage.haskell.org/package/elynx-tools) -   [elynx-tree](https://hackage.haskell.org/package/elynx-tree) -Documentation of the executables is, or course, also available:+Documentation of the executables is also available: +-   [elynx](https://hackage.haskell.org/package/elynx) -   [slynx](https://hackage.haskell.org/package/slynx) -   [tlynx](https://hackage.haskell.org/package/tlynx) 
app/Main.hs view
@@ -166,7 +166,7 @@ runRedo :: RedoArguments -> IO () runRedo a = do   let fp = rElynxFile a-  let f = rForce a+  let f  = rForce a   when (f == Force False) $ do     putStrLn "Validate ELynx reproduction file before reanalysis."     putStrLn "Use the --force (-f) option to skip this test."
elynx.cabal view
@@ -1,6 +1,6 @@ cabal-version: 1.12 name: elynx-version: 0.2.1+version: 0.2.2 license: GPL-3 license-file: LICENSE copyright: Dominik Schrempf (2020)@@ -34,7 +34,7 @@         aeson >=1.4.7.1 && <1.5,         base >=4.13.0.0 && <4.14,         bytestring >=0.10.10.0 && <0.11,-        elynx-tools >=0.2.1 && <0.3,+        elynx-tools >=0.2.2 && <0.3,         optparse-applicative >=0.15.1.0 && <0.16,-        slynx >=0.2.1 && <0.3,-        tlynx >=0.2.1 && <0.3+        slynx >=0.2.2 && <0.3,+        tlynx >=0.2.2 && <0.3